Review Article

Helicobacter pylori: Genomic Insight into the Host-Pathogen Interaction

Figure 2

High resolution scanning electron micrograph of H. pylori in contact with human gastric epithelial cells. H. pylori virulence factors including flagella (black arrows) and cag-T4SS pili (white arrows) are present on the bacterial cell surface during host-pathogen interaction. Flagella aid in cell motility through the mucus layer to penetrate host tissues. The cag-T4SS pili induce proinflammatory and oncogenic cellular responses. Magnification bar indicates 1 μm.