Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location

Figure 5

Polymorphic MLV-ERV landscapes of spatially separated organ sets of a C57BL/6J mouse. There were considerable variations in MLV-ERV landscapes among the individual sets of three lymph nodes (thoracic mammary, inguinal mammary, and mesenteric) and two mammary fat pads (number 2 right and number 4 right) derived from a female C57BL/6J mouse. In contrast, bone marrow samples isolated from the left and right femurs shared I-PCR amplicon patterns which are visibly different (density and banding pattern) from the landscapes of lymph nodes and mammary fat pads. A selected area is shown as a reversed image for better analysis. SM: size marker; TM-LN: thoracic mammary lymph node; IM-LN: inguinal mammary lymph node; FP: fat pad; L: left; R: right; BM: bone marrow.