Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location

Figure 6

Variable MLV-ERV landscapes in C57BL/6J inbred mice depending on gender, individual, and organ type. There were apparent variations in MLV-ERV landscapes of the kidney and liver genomes between females and males of C57BL/6J mice; these variations include one distinct I-PCR amplicon band (indicated with an arrow) found only in male mice. In addition, MLV-ERV landscapes of the liver genomes lack a set of amplicon bands in contrast to the kidney genomes (). Furthermore, each mouse (female or male) had either one of the two distinct sets of I-PCR amplicon bands, regardless of gender (). A reversed image of a selected area (indicated with an arrowed dotted line) is also presented. SM: size marker; KI: kidney; LI: liver; F: female; M: male.