Research Article

A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis

Table 1

The annotation of the top 20 miRNAs in AML.

Cancer typeNumber of genesDisease

AMLhsa-mir-556170
hsa-mir-217163B-cell chronic lymphocytic leukemia, pancreatic neoplasms, nasopharyngeal carcinoma
hsa-mir-636159Myelodysplastic syndromes, multiple myeloma
hsa-mir-320c-1147Hepatocellular carcinoma, interstitial cystitis
hsa-mir-639145Lung cancer, gastric cancer, breast cancer
hsa-mir-873145Glioblastoma, endometriosis
hsa-mir-573138Pancreatic cancer, esophageal cancer, breast cancer
hsa-mir-216b116Lung neoplasms, nasopharyngeal neoplasms, colorectal neoplasms
hsa-mir-605109Stomach neoplasms, ovarian cancer
hsa-mir-188103B-cell chronic lymphocytic leukemia, salivary gland neoplasms, rectal neoplasms
hsa-mir-146889
hsa-mir-29652Glioma, prostate cancer, urinary bladder neoplasms
hsa-mir-48849Melanoma, ovarian neoplasms, prostatic neoplasms
hsa-mir-125b-140Acute myeloid leukemia, breast neoplasms, hepatocellular carcinoma
hsa-mir-50236Colonic neoplasms, ovarian neoplasms, hepatocellular carcinoma
hsa-mir-551a32Stomach neoplasms, ovarian cancer
hsa-mir-10030Acute myeloid leukemia, precursor cell lymphoblastic leukemia-lymphoma, endometrial neoplasms
hsa-mir-50129Melanoma, atrophic muscular disorders
hsa-mir-520a26Hodgkin’s lymphoma, stomach neoplasms, colorectal neoplasms
hsa-mir-181d25Acute myeloid leukemia, acute promyelocytic leukemia, glioblastoma

The miRNA was directly associated with AML. No description of the miRNA was found in the disease-related miRNA database.