A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis

Table 4

The top 5 KEGG pathways enriched with the genes connected with the cancer-specific miRNAs.

Cancer type	KEGG pathways	value
AML	hsa00980: metabolism of xenobiotics by cytochrome	0.0241
	hsa00982: drug metabolism	0.0263
	hsa04740: olfactory transduction	0.0407
BRCA	hsa04080: neuroactive ligand-receptor interaction
	hsa00140: steroid hormone biosynthesis	0.0120
	hsa03320: PPAR signaling pathway	0.0176
	hsa04610: complement and coagulation cascades	0.0176
	hsa00150: androgen and estrogen metabolism	0.0246
KIRC	hsa05322: systemic lupus erythematosus	0.0003
	hsa04060: cytokine-cytokine receptor interaction	0.0021
	hsa04740: olfactory transduction	0.0122
	hsa05034: alcoholism	0.0219
	hsa00350: tyrosine metabolism	0.0224

The pathway was directly associated with the corresponding cancer type. The pathway was associated with other cancers.