A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis

Table 6

The annotation of the key genes connected with more than three cancer-specific miRNAs in the miRNA-mRNA interaction networks.

Cancer type	Gene	Gene description	Protein class
AML	ASPG	Asparaginase	Enzymes, predicted intracellular proteins
BRCA	AQP2	Aquaporin 2 (collecting duct)	Disease-related genes, potential drug targets, predicted membrane proteins, transporters
KIRC	CNOT8	CCR4-NOT transcription complex subunit 8	Enzymes, plasma proteins, predicted intracellular proteins
	CTPS1	CTP synthase 1	Disease-related genes, enzymes, potential drug targets, predicted intracellular proteins
	IFNAR2	Interferon (alpha, beta, and omega) receptor 2	Cancer-related genes, FDA-approved drug targets, predicted intracellular proteins, predicted membrane proteins
	MOCS2	Molybdenum cofactor synthesis 2	Disease-related genes, enzymes, potential drug targets, predicted intracellular proteins
	PRSS37	Protease, serine 37	Enzymes, predicted secreted proteins
	VCP	Valosin-containing protein	Disease-related genes, enzymes, plasma proteins, potential drug targets, predicted intracellular proteins, transporters