Research Article

Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans

Figure 2

Venn-diagram of stress-responsive genes. (a) Distribution of stress-responsive (upregulated/downregulated) genes among the 3 oxidative stresses in the control strain. (b) Distribution of stress-responsive (upregulated/downregulated) genes among the 3 oxidative stresses in the ΔatfA strain. (c) Distribution of AtfA-dependent genes (showing upregulation/downregulation in the control strain) according to their stress dependence lost in the mutant strain. (d) Distribution of coregulated genes between the two strains. Stress-responsive, upregulated, downregulated, AtfA-dependent, and coregulated genes are defined in Materials and Methods.
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