International Journal of Genomics / 2018 / Article / Tab 5 / Research Article
Gene Variation of Endoplasmic Reticulum Aminopeptidases 1 and 2, and Risk of Blood Pressure Progression and Incident Hypertension among 17,255 Initially Healthy Women Table 5 Cross-reference comparison for specific ERAP1 and ERAP2 gene variants.
Present study Yamamoto et al. [11 ] Yang et al. [42 ] Johnson et al. [9 ] Johnson et al. [9 ] Hill et al. [8 ] Hill et al. [8 ] Outcome Incident hypertension Hypertension Hypertension Preeclampsia Preeclampsia Preeclampsia Preeclampsia Sample population US White females Japanese case/control Northeastern Han Chinese case/control Australian/New Zealand familial cohort Norwegian case/control Chilean maternal-fetal dyads Unpaired African-American Sample size 17,255 143/348 300/233 74 families 1139/2269 1103 maternal–fetal dyads 836 maternal dbSNP ERAP1 rs30187 — — — — — rs26618 ns — — — — — rs27980 — — — — — — rs17086651 — — — — — — rs3734016 — — — — — rs34750 — — — — — — ERAP2 rs2549782 — — — ns rs17408150 — — — ns Not further evaluated due to allelic rarity
HR = hazard ratio; OR = odds ratio; CI = confidence interval; ns = nonsignificant.
