Differential Expression Profiling of Long Noncoding RNA and mRNA during Osteoblast Differentiation in Mouse

Figure 3

WGCNA analysis of 4058 time series gene expression data at the nine time points of osteoblast differentiation. (a) Hierarchical cluster trees depict coexpression modules identified using WGCNA. (b) A heat map plot of module-trait association. Each row corresponds to the module eigengene, the first principal component of a module. Each column corresponds to trait, the nine time points of osteoblast differentiation (days 2, 4, 6, 8, 10, 12, 14, 16, and 18). Each cell contains the corresponding correlation value and value (left panel). Each of the sixteen modules contains between 16 and 819 genes (right panel). (c) Functional annotations of cyan and salmon modules. Gene ontology (GO) and KEGG pathway terms and corresponding values are shown.

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