Review Article
Genetic Polymorphisms in the RAD51 Gene with a Risk of Head and Neck Cancer and Esophageal Cancer: A Meta-Analysis
Table 2
Characteristics of included studies for RAD51 polymorphisms.
| | SNP | First name (year) | Cases (GG/GC/CC) | Controls (GG/GC/CC) | Cases (G/C-allele) | Controls (G/C-allele) | (HWE) | NOS score | | 135G/C | Lu (2007) | 624/91/1 | 622/96/1 | 1339/93 | 1340/98 | 0.170 | 7 | | | Werbrouck (2008) | 136/15/1 | 134/23/0 | 287/17 | 291/23 | 0.322 | 7 | | | Sliwinski (2010) | 101/88/2 | 258/64/32 | 290/92 | 580/128 | <0.001 | 8 | | | Gresner (2012) | 67/13/1 | 71/14/2 | 147/15 | 156/18 | 0.217 | 8 | | | Romanowicz-Makowska (2012) | 174/69/10 | 190/58/5 | 417/89 | 438/68 | 0.816 | 7 | | | Xue-Jiao (2013) | 83/35/5 | 54/6/1 | 201/45 | 114/8 | 0.123 | 6 | | | Shu-Xiang (2014) | 206/100/10 | 216/92/8 | 512/120 | 524/108 | 0.626 | 7 | | | Kayani (2014) | 120/70/10 | 106/41/3 | 310/90 | 253/47 | 0.674 | 7 | | | Ming-Zhong (2014) | 144/56/19 | 223/24/11 | 344/94 | 470/46 | <0.001 | 7 | | | Santos (2018) | 110/16/0 | 111/17/2 | 236/16 | 239/21 | 0.174 | 8 |
| | | | Cases (GG/GT/TT) | Controls (GG/GT/TT) | Cases (G/T-allele) | Controls (G/T-allele) | | | | 172G/T | Lu (2007) | 261/351/104 | 240/335/144 | 873/559 | 815/623 | 0.169 | 7 | | | Gresner (2012) | 36/43/2 | 43/54/13 | 115/47 | 140/80 | 0.524 | 8 | | | Kayani (2014) | 83/90/27 | 99/49/2 | 256/144 | 247/53 | 0.132 | 7 | | | Santos (2018) | 51/52/23 | 51/56/23 | 154/98 | 158/102 | 0.271 | 8 |
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