Genetic Polymorphisms in the RAD51 Gene with a Risk of Head and Neck Cancer and Esophageal Cancer: A Meta-Analysis
Table 5
False-positive report probability values for the rs1801320 and rs1801321 gene polymorphisms.
Variables
OR (95% CI)
a
Powerb
Prior probability
0.25
0.1
0.01
0.001
0.0001
rs1801320
C versus G
Overall
1.32 (1.03-1.71)
0.036
0.833
0.113
0.277
0.808
0.977
0.998
PCR-RFLP
1.52 (1.15-2.02)
0.004
0.464
0.025
0.070
0.455
0.894
0.988
Asian
1.89 (1.16-3.08)
0.011
0.177
0.153
0.351
0.856
0.984
0.998
Large sample
1.41 (1.02-1.96)
0.041
0.644
0.160
0.364
0.863
0.984
0.998
EC
2.07 (1.01-4.25)
0.047
0.190
0.428
0.692
0.961
0.996
1.000
CC versus GG
Asian
2.20 (1.30-3.74)
0.004
0.079
0.120
0.291
0.819
0.979
0.998
EC
2.08 (1.17-3.71)
0.013
0.134
0.227
0.468
0.906
0.990
0.999
CG versus GG
Overall
1.50 (1.03-2.19)
0.036
0.500
0.177
0.391
0.876
0.986
0.999
PCR-RFLP
1.84 (1.19-2.86)
0.007
0.182
0.100
0.250
0.786
0.974
0.997
Asian
2.20 (1.30-3.74)
0.004
0.079
0.120
0.291
0.819
0.979
0.998
Large sample
1.75 (1.01-3.01)
0.043
0.289
0.309
0.579
0.937
0.993
0.999
CC+CG versus GG
Overall
1.44 (1.05-1.99)
0.027
0.598
0.120
0.290
0.818
0.978
0.998
PCR-RFLP
1.74 (1.20-2.51)
0.003
0.214
0.041
0.114
0.585
0.934
0.993
Asian
2.06 (1.17-3.64)
0.013
0.137
0.219
0.457
0.902
0.989
0.999
Large sample
1.61 (1.04-2.51)
0.036
0.377
0.220
0.459
0.903
0.989
0.999
CC versus CG+GG
Asian
1.89 (1.12-3.19)
0.017
0.193
0.210
0.444
0.898
0.989
0.999
EC
1.78 (1.00-3.15)
0.048
0.278
0.340
0.607
0.944
0.994
0.999
rs1801321
T versus G
Caucasian
0.82 (0.72-0.95)
0.008
0.997
0.024
0.069
0.449
0.892
0.988
aChi-square test was adopted to calculate the genotype frequency distributions. bStatistical power was calculated using the number of observations in the subgroup and the OR and values in this table.
