Research Article
Research and Discussion on the Relationships between Noise-Induced Hearing Loss and ATP2B2 Gene Polymorphism
Table 4
Stratified analysis of SNPs in the allelic model.
| SNPs | Group | Alleles | Cumulative noise exposure (dBA) | ≤95 | >95 |
| rs1719571 | Case group | G | 67 | 228 | | A | 109 | 356 | Control group | G | 43 | 228 | | A | 91 | 398 | a | | 0.276 | 0.373 | Adjusted OR (95% CI)b | | 1.32 (0.82-2.13) | 1.12 (0.89-1.42) |
| rs14154 | Case group | G | 70 | 241 | | C | 106 | 343 | Control group | G | 47 | 240 | | C | 87 | 386 | a | | 0.398 | 0.298 | Adjusted OR (95% CI)b | | 1.24 (0.77-1.98) | 1.14 (0.91-1.44) |
| rs3209637 | Case group | C | 88 | 303 | | T | 88 | 281 | Control group | C | 71 | 281 | | T | 63 | 345 | a | | 0.602 | 0.015 | Adjusted OR (95% CI)b | | 0.90 (0.57-1.42) | 1.34 (1.07-1.68) |
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aTwo-sided test. bAdjusted for age, sex, tobacco use, and alcohol consumption in logistic regression model. |