Positive Selection of Squalene Synthase in Cucurbitaceae Plants

Figure 6

Sites of positive selection (52A, 180L, 189S, 196S, 200S, and 289P) on the GpSS model using DSV. (a) 180Leu was connected with FPP, 66Val, 184Phe, and 285Phe by nonbonded interactions. (b) 52Ala and 289Pro were connected with FPP and 51Phe. (c, d) Distribution of 189Ser, 196Ser, and 200Ser and 289Pro on the GpSS 3D structure. Yellow areas indicate transmembrane domains. (e) Relationship between GpSS receptors and ligands (FPP). Dashed lines indicate nonbonded interactions.

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