Research Article
An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene
Table 3
Docking analysis of native and mutant complexes.
| Protein (receptor) | Ligand | Global binding energy |
| Native MET receptor | NK1 | −4.00 | NK2 | −8.41 | Mutant A238S | NK1 | −4.00 | NK2 | −8.41 | Mutant A320V | NK1 | −0.60 | NK2 | −8.41 | Mutant P239R | NK1 | −4.00 | NK2 | −8.41 | Mutant A364T | NK1 | 6.31 | NK2 | −8.41 | Mutant D340G | NK1 | −4.00 | NK2 | −8.41 | Mutant T222M | NK1 | −4.00 | NK2 | −11.86 |
|
|