An Investigation of the Prognostic Role of Genes Related to Lipid Metabolism in Head and Neck Squamous Cell Carcinoma

Figure 2

Establishment of the HNSCC risk model. (a) Construction of eight prognosis genes (PHYH, CYP4F8, INMT, ELOVL6, PLPP3, BCHE, TPTE, and STAR) by multivariate Cox. (b and c) Kaplan–Meier curves of the eight-gene signature in the training and testing set. (d and e) The AUC of the ROC curve in the training set and testing set was 0.695 and 0.657, respectively. (f) The expression patterns of eight identified DELMRGs for the patients in the training set (left). The distribution of risk score (top right) and vital status (bottom right) of patients in the training set. (g) The heatmap of mRNA expression of the eight-gene signature (left) and the distribution of risk score (right) in the testing set.

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