An Investigation of the Prognostic Role of Genes Related to Lipid Metabolism in Head and Neck Squamous Cell Carcinoma

Table 4

Association between ELOVL6 expression and clinicopathological features in OSCC.

Characteristics	n	ELOVL6 expression (%)		χ^2	-value
		Low	High
Total	71	49 (69)	22 (31)
Sex
Male	50	33 (66.0)	17 (34.0)	0.718	0.397
Female	21	16 (76.2)	5 (23.8)
Age
<60	25	19 (76.0)	6 (24.0)	0.881	0.348
≥60	46	30 (65.2)	16 (34.8)
Localization
Tongue	29	19 (65.5)	10 (34.5)	2.374	0.491
Buccal mucosa	21	16 (76.2)	5 (23.8)
Gingiva	13	10 (76.9)	3 (23.1)
Other^a	8	4 (50.0)	4 (50.0)
Perineural infiltration
Yes	20	14 (70.0)	6 (30.0)	0.013	0.910
No	51	35 (68.6)	16 (31.4)
Vascular invasion
Yes	7	4 (57.1)	3 (42.9)	—	0.669
No	64	45 (70.3)	19 (29.7)
TNM
I	38	31 (81.6)	7 (18.4)	6.036	0.014^b
II + III	33	18 (54.5)	15 (45.5)
Tumor size
T1 ≤ 2 cm	12	9 (75.0)	3 (25.0)	1.805	0.649
2 cm < T2 ≤ 4 cm	36	26 (72.2)	10 (27.8)
T3 > 4 cm	10	7 (70.0)	3 (30.0)
T4	13	7 (53.8)	6 (46.2)
Lymph node metastases
N0	39	26 (66.7)	13 (33.3)	0.464	0.885
N1	19	13 (68.4)	6 (31.6)
N2	13	10 (76.9)	3 (23.1)
N3	0	0	0
Distant metastases
M0	71	49 (69.0)	22 (31.0)	—	—
M1	0	0	0

^aOther: carcinoma of the palate five cases and lip carcinoma three cases.
^b.