Milan Criteria and UCSF Criteria: A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States
Table 1
Characteristics of patients within the cohort.
Clinicopathologic factors
N = 1972
Age (yrs)
Mean ± SD (Range)
56 ± 8 (18–78)
≤50
441 (22)
51–64
1211 (61%)
≥65
337 (17%)
Gender
Female
418 (21%)
Male
1571 (79%)
Diabetes mellitus
No
1475 (74%)
Yes*
481 (24%)
Unknown
33 (2%)
BMI
Mean, ±SD
28.1 (4.9)
Range
(13–51)
<30
1380 (69%)
≥30
596 (30%)
Unknown
13 (1%)
Hepatitis B Virus
Negative
1111 (56%)
Positive
662 (33%)
Unknown
216 (11%)
Hepatitis C Virus
Negative
639 (33%)
Positive
1130 (57%)
Unknown
220 (11%)
Number of tumors
Mean (range)
1 ± 0.7 (1–5)
1
1343 (67%)
2
452 (23%)
3
191 (10%)
4
2 (0%)
5
1 (0%)
Total Tumor Diameter (cm)
Mean ± SD (range)
3 ± 1 (0.2–17)
Vital status
Alive
1479 (74%)
Dead
510 (26%)
COD
Malignancy recurrence
160 (31%)
Other
284 (56%)
Unknown
66 (13%)
Liver Directed Therapy†
No
1274 (64%)
Yes
715 (36%)
Transplant criteria
Milan
1913 (96%)
UCSF
59 (3%)
*Diabetes mellitus Type I or II; or type unknown. †Radiofrequency ablation, transarterial chemoembolization, cryoablation. BMI: body mass index; COD: cause of death.
