Clinical Study
Milan Criteria and UCSF Criteria: A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States
Table 2
Comparison of patient characteristics by transplant criteria.
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Factors | Transplant criteria | | Milan | UCSF | P value | (N = 1913 ) | (N = 59) |
| Age (yrs) | | | | Mean, ± SEM | 56.2 ± 0.18 | 58.4 ± 1.02 | | ≤50 | 426 (22%) | 11 (19%) | 0.11 | 51–64 | 1169 (61%) | 32 (54%) | | ≥65 | 318 (17%) | 16 (27%) | | Gender | | | 0.87 | Female | 399 (21%) | 13 (22%) | Male | 1514 (79%) | 46 (78%) | Diabetes mellitus | | | 0.47 | No | 1418 (75%) | 43 (77%) | Yes* | 465 (25%) | 13 (23%) | BMI | | | 0.59 | Mean, ±SEM | 28.1 ± 0.11 | 28.4 ± 0.66 | Liver directed therapy | | | <0.001 | No | 1243 (65%) | 23 (39%) | Yes | 670 (35%) | 36 (61%) | Number of tumors | | | <0.001 | 1 | 1316 (69%) | 23 (39%) | 2 | 420 (22%) | 26 (44%) | 3 | 177 (9%) | 10 (17%) | Vital status | | | 0.37 | Alive | 1426 (74%) | 41 (70%) | Dead | 487 (26%) | 18 (30%) | Hepatitis C Virus | | | 0.45 | Negative | 615 (36%) | 20 (42%) | Positive | 1094 (64%) | 28 (58%) | Hepatitis B Virus | | | 0.88 | Negative | 1073 (63%) | 30 (61%) | Positive | 639 (37%) | 19 (39%) | Total Tumor Diameter | | | <0.001 | Mean ± SEM | 3.27 ± 0.03 | 5.86 ± 0.09 | COD | | | 0.01
| Malignancy recurrence | 149 (35%) | 9 (69%) | Other | 278 (65%) | 4 (31%) |
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*Yes: type I or II; or type unknown. SEM: standard error of the mean; BMI: body mass index; COD: cause of death.
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