Milan Criteria and UCSF Criteria: A Preliminary Comparative Study of Liver Transplantation Outcomes in the United States

Table 2

Comparison of patient characteristics by transplant criteria.

Factors	Transplant criteria
	Milan	UCSF	P value
	(N = 1913 )	(N = 59)
Age (yrs)
Mean, ± SEM	56.2 ± 0.18	58.4 ± 1.02
≤50	426 (22%)	11 (19%)	0.11
51–64	1169 (61%)	32 (54%)
≥65	318 (17%)	16 (27%)
Gender			0.87
Female	399 (21%)	13 (22%)
Male	1514 (79%)	46 (78%)
Diabetes mellitus			0.47
No	1418 (75%)	43 (77%)
Yes*	465 (25%)	13 (23%)
BMI			0.59
Mean, ±SEM	28.1 ± 0.11	28.4 ± 0.66
Liver directed therapy			<0.001
No	1243 (65%)	23 (39%)
Yes	670 (35%)	36 (61%)
Number of tumors			<0.001
1	1316 (69%)	23 (39%)
2	420 (22%)	26 (44%)
3	177 (9%)	10 (17%)
Vital status			0.37
Alive	1426 (74%)	41 (70%)
Dead	487 (26%)	18 (30%)
Hepatitis C Virus			0.45
Negative	615 (36%)	20 (42%)
Positive	1094 (64%)	28 (58%)
Hepatitis B Virus			0.88
Negative	1073 (63%)	30 (61%)
Positive	639 (37%)	19 (39%)
Total Tumor Diameter			<0.001
Mean ± SEM	3.27 ± 0.03	5.86 ± 0.09
COD			0.01
Malignancy recurrence	149 (35%)	9 (69%)
Other	278 (65%)	4 (31%)

*Yes: type I or II; or type unknown.
SEM: standard error of the mean; BMI: body mass index; COD: cause of death.