Towards Noninvasive Detection of Oesophageal Varices

Table 1

Summary of diagnostic accuracy of LSM for the detection of oesophageal varices (OV) or large varices (LOV). TE: transient elastography.

Diagnostic performance of TE for the diagnosis of OV by Author	[54]	[55]	[56]	[57]	[47]
Number of pts	165	61 (47 cirrhotic)	150 (89 cirrhotic)	112	298 (70 cirrhotic)
Aetiology	Mixed (HCV predominant)	HCV	Mixed	Mixed	HCV
Prevalence OV	45%	64%	72%		36%
Proposed cutoffs forpresence of OV/LOV	OV 13.1; LOV 19	17.6	OV 21.1; LOV 29.3	19.7	OV 21.5; LOV 30.5
Sensitivity (%)	95/91	90	84/81	87	76/77
Specificity (%)	43/60	43	71/61	70	78/85
PPV (%)	57/48	77		89	68/56
NPV (%)	91/95	66		66	84/94
AUROC	0.84/0.83	0.76	0.85/0.76	0.818	0.84/0.87