Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy
Figure 3
Biliary epithelial autophagy in PBC. (a) The expression of autophagy marker LC3 was not observed in BECs in noninflammed bile ducts (arrow) in PBC. (b) The expression of autophagy marker LC3 was detected in intracytoplasmic vesicles (arrows) in BECs involved in inflamed and damaged small bile ducts in PBC. Immunostaining for LC3. Original magnification, ×400 (inset, ×1000).
