Cholangiopathy with Respect to Biliary Innate Immunity
Figure 1
Immunohistochemistry for TLR3 in chronic hepatitis C (a) and TLR4 in primary biliary cirrhosis (PBC). The expression of TLR3 existing in endosomes is found in interlobular bile ducts (arrow in (a)) and hepatocytes in a cytoplasmic pattern. In contrast, TLR4 expression is highlighted in a membranous pattern (b).