Research Article

Betaine Treatment Attenuates Chronic Ethanol-Induced Hepatic Steatosis and Alterations to the Mitochondrial Respiratory Chain Proteome

Figure 1

Betaine attenuates chronic ethanol-dependent steatosis. Hematoxylin-eosin (A) and BODIPY 493/503-DAPI (B, green BODIPY-labeled lipid droplets, nuclei blue) stained images from representative livers of (a) control; (b) control + betaine; (c) ethanol; (d) ethanol + betaine rats ( rats’/group) fed the respective diets for 4-5 weeks. Liver sections of the representative ethanol-fed rat stained with hematoxylin-eosin or BODIPY 493/503-DAPI shows micro- and macrovesicular steatosis (arrows).
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