Review Article

Treatment of Neuroendocrine Tumor Liver Metastases

Table 4

Summary of outcomes for liver transplantation for neuroendocrine metastases.

Author, publication yearNumber of liver transplant (LT) patientsSurvival dataPredictors of survival

Gedaly et al., 2011 [34]150
(13 receiving another organ at time of LT)
49% 5-year survivalImproved survival with patients waiting more than 2 months for transplant ( ), esp. in patients >55 years old

Mathe et al., 2011 [35]8944% 5-year survival0% survival if >55 years old undergoing simultaneous pancreatic resection

Le Treut et al., 2008 [36]85
(34 with concurrent extrahepatic resection)
Median OS: 56 months Exenteration, duodeno-pancreatic primary, and hepatomegaly were indicators of poor prognosis (all RR of death > 2.6)

Rosenau et al., 2002 [37]1950% 10-year survival Ki-67 <5% and normal E-cadherin expression had 100% 7-year survival