Pretreatment of Small-for-Size Grafts In Vivo by γ-Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation

Figure 4

Immunohistological assessment by caspase 3. (a) Laparotomy with saline: caspase 3, ×100. (b) SOLT with saline: caspase 3, ×100. (c) SOLT with GABAR agonist: caspase 3, ×100. (d) The ratio of caspase 3-positive nuclei. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05^†). Caspase, cysteine aspartic acid protease; GABAR, γ-aminobutyric acid receptor; HV, hepatic vein; SFSG, small-for-size graft; SOLT, split orthotopic liver transplantation; and PV, portal vein.

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