Pretreatment of Small-for-Size Grafts In Vivo by γ-Aminobutyric Acid Receptor Regulation against Oxidative Stress-Induced Injury in Rat Split Orthotopic Liver Transplantation

Figure 6

Western blot analyses of ATM and H2AX. (a) Intensities of ATM, H2AX, and GAPDH. (b) Normalized ATM. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05^†). (c) Normalized H2AX. There were significant differences between laparotomy and SOLT with saline (𝑃<0.05*) and between SOLT with saline and SOLT with GABAR agonist (𝑃<0.05^†). ATM, ataxia-telangiectasia mutated kinase; GABAR, γ-aminobutyric acid receptor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; SFSG, small-for-size graft; and SOLT, split orthotopic liver transplantation.

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