Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context
Figure 7
Rare, misleading cytological findings. (a) Woman born in 1964. Abnormal liver tests and anemia. No oral contraceptives, BMI 40.4. Alcohol (30 to 40 g per day), hypercholesterolemia, and type 2 diabetes. Biopsy: IHCA. Right hepatectomy 2006: IHCA. The anemia corrected several months after surgery. Perls staining: positivity in sinusoidal cells of the IHCA. (b) Woman born in 1936. Oral contraceptives 21 years. Several liver nodules. Tumorectomies in 1989. H&E: numerous epithelioid granulomas are widespread within the IHCA. (c-d): Woman born in 1947. Massive bleeding. No oral contraceptives, BMI 21.5. Right hepatectomy 2000. Massive liver necrosis. Pathological diagnosis: IHCA. H&E: areas with cytological abnormalities: dystrophic nuclei (irregular, hyperchromatic), nearby necrotic/hemorrhagic zones of the IHCA.
