Research Article

Focal Nodular Hyperplasia and Hepatocellular Adenoma around the World Viewed through the Scope of the Immunopathological Classification

Table 1

Diagnosis of FNH and HCA performed in different academic centers.

HCAFNHNo final diagnosis
Surgery Biopsy Surgery Biopsy Surgery Biopsy

French (from 2008 to 2011)
(1) Besançon4 (4♀)1013300
(2) Bordeaux49 (44♀)16272902
(3) Caen22 (20♀)619600
(4) Créteil14 (13♀)
2 with HCC
19
3 with HCC
191300
(5) Grenoble19 (18♀)1831201
(6) Lille31 (26♀)
1 with HCC
30253926
(7) Lyon (1)49 (41♀)
4 with HCC
13171647
(1 with HCC)
(8) Lyon (2)16 (13♀)
1 with HCC
25142204
(9) Montpellier32 (31♀)
1 with HCC
28152531
(10) Nice32 (31♀)
1 with HCC
2832531
(11) Paris (St. Antoine)11 (9♀)
1 with HCC
13201402
(1 with HCC)
(12) Villejuif (Gustave Roussy)1 (1♀)35 (4♀)604

International

(1) Baltimore (from 1984 to 2012)63 (61♀)
7 with HCC
6795448
(2) Brussels
  (Cliniques universitaires
  Saint-Luc-UCL)
  (1992–2012)*
37 (33♀): 21 IHCA, 10 H-HCA, 1 with IHCA + H-HCA, 3  β-HCA (2 with HCC), 2 UHCA142214
(3) Heidelberg (2007–2011)11 (11♀): 9 IHCA, 1 H-HCA, 1 with IHCA + H-HCA34
(4) London Kings (1998–2011)35 (30♀): 18 IHCA, 7 H-HCA, 1  β-HCA, 9 UHCA
(5) NY (Mt Sinai) (2007–2011)*27: 9 H-HCA, 11 I-HCA, 7 UHCA15
(6) San Francisco
 (selected cases)
12 (10♀): 2 IHCA, 3 H-HCA (1 with HCC, 1 borderline), 3  β-HCA (2 with HCC, 1 borderline), 4 UHCA (1 with HCC)
(7) Seattle (2008–2011)9 (7♀): 3 IHCA, 3 H-HCA, 1  β-HCA, 2 UHCA11
(8) Seoul (2008–2011)2 (1♀): 1  β-IHCA, 1  β-HCA (1 with HCC)4 (3♀)
(9) Singapore (selected cases)2 (2♀): 1  β-IHCA (with HCC), 1 H-HCA
(10) Taiwan12 (5♀): 3 IHCA, 2  β-HCA, 1 H-HCA, 6 UHCA

See papers in this issue for additional information.