Review Article

Diagnosis and Management of Giant Hepatic Hemangioma: The Usefulness of Contrast-Enhanced Ultrasonography

Figure 4

Intranodular dynamic image of the hepatic hemangioma in tumor 2. (a) B-mode US shows a nonhomogeneously hyperechoic lesion approximately 6 cm in size in the right lobe of the liver. (b) Sonazoid contrast-enhanced US in the early vascular phase reveals typical “peripheral globular enhancement” of the lesion. (c) The lesion shows progressive “partial centripetal filling-in” during the late vascular phase. (d) The tumor is visualized as a hypoperfusion image in the Kupffer phase. (e) The same pattern is apparent 20 s after reinjection of Sonazoid: typical “peripheral globular enhancement” of the lesion in the early vascular phase 20 s after the first injection of Sonazoid. (f) Parenchymal perfusion 13 min after reinjection results in a hypoperfusion image similar to that in the Kupffer phase after the first injection of Sonazoid.
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