Immunohistochemical phenotypes in intraductal papillary neoplasms of the bile duct (IPNB) and intraductal papillary mucinous neoplasms of the pancreas (IPMN) [16, 33].
Epithelial subtypes
Mucin core proteins
Cytokeratin (CK)
MUC1
MUC2
MUC5AC
CK20
CK7
IPNB
IPMN
IPNB
IPMN
Gastric
−
−
+
0 (0/5)*
0 (0/10)
100 (5/5)
80 (8/10)
Intestinal
−
+
+
75 (3/4)
71 (12/17)
50 (2/4)
82 (14/17)
Pancreatobiliary
+
−
+
22 (2/9)
0 (0/2)
78 (7/9)
100 (2/2)
Oncocytic
+
0 (0/2)
N.D.
50 (1/2)
N.D.
*% of positive cases (positive cases/total cases examined); N.D.: not determined.
