Fructose Induced Endotoxemia in Pediatric Nonalcoholic Fatty Liver Disease

Table 1

Anthropometrics and laboratory parameters of the 32 adolescents with hepatic steatosis and the 11 obese controls at fasting state: study cohort 1.

Parameters, mean (SD)	Obese controls	Subjects with steatosis	value
	(<5% by MRS, )	(>5% by MRS, )
Age, years	14.3 (1.85)	13.7 (2.65)	0.443
Male (, %)	4 (36.4)	13 (40.6)	0.803
Weight (kg)	82.9 (21.5)	80.5 (14.9)	0.967
BMI -score	2.00 (0.22)	2.17 (0.37)	0.129
ALT (U/L)	17.8 (7.60)	49.7 (89.5)	0.021
AST (U/L)	21.9 (3.99)	68.2 (180)	<0.001
Hepatic fat (%)	3.87 (0.62)	11.2 (5.27)	<0.001
Glucose (mmol/L)	5.13 (0.89)	5.18 (0.90)	0.978
Insulin (mU/L)	18.2 (6.69)	36.2 (30.5)	0.010
HOMA-IR	4.06 (1.31)	8.79 (9.13)	0.013
hs-CRP (mg/L)	3.17 (3.44)	4.98 (5.92)	0.278

BMI: body mass index; ALT: alanine aminotransferase; AST: aspartate aminotransferase; HOMA-IR: homeostatic model assessment for insulin resistance, calculated as fasting glucose (mmol/L) × insulin (mU/L)/22.5; hs-CRP: high sensitivity C-reactive protein.