Fructose Induced Endotoxemia in Pediatric Nonalcoholic Fatty Liver Disease
Table 1
Anthropometrics and laboratory parameters of the 32 adolescents with hepatic steatosis and the 11 obese controls at fasting state: study cohort 1.
Parameters, mean (SD)
Obese controls
Subjects with steatosis
value
(<5% by MRS, )
(>5% by MRS, )
Age, years
14.3 (1.85)
13.7 (2.65)
0.443
Male (, %)
4 (36.4)
13 (40.6)
0.803
Weight (kg)
82.9 (21.5)
80.5 (14.9)
0.967
BMI -score
2.00 (0.22)
2.17 (0.37)
0.129
ALT (U/L)
17.8 (7.60)
49.7 (89.5)
0.021
AST (U/L)
21.9 (3.99)
68.2 (180)
<0.001
Hepatic fat (%)
3.87 (0.62)
11.2 (5.27)
<0.001
Glucose (mmol/L)
5.13 (0.89)
5.18 (0.90)
0.978
Insulin (mU/L)
18.2 (6.69)
36.2 (30.5)
0.010
HOMA-IR
4.06 (1.31)
8.79 (9.13)
0.013
hs-CRP (mg/L)
3.17 (3.44)
4.98 (5.92)
0.278
BMI: body mass index; ALT: alanine aminotransferase; AST: aspartate aminotransferase; HOMA-IR: homeostatic model assessment for insulin resistance, calculated as fasting glucose (mmol/L) × insulin (mU/L)/22.5; hs-CRP: high sensitivity C-reactive protein.