Fructose Induced Endotoxemia in Pediatric Nonalcoholic Fatty Liver Disease

Table 2

Baseline characteristics of the 8 adolescents with biopsy-proven NAFLD and the 7 healthy controls: study cohort 2.

Parameters, mean (SD)	non-NAFLD ()	NAFLD ()	value
Age, years	13.7 (2.22)	13.0 (2.73)	0.315
Male, (%)	5 (71.4)	8 (100)	0.104
BMI -score	0.18 (0.65)	2.29 (0.38)	0.001
Hepatic fat, %	1.02 (1.18)	22.0 (6.16)	0.001
ALT (U/L)	14.6 (2.51)	130 (63.2)	0.001
AST (U/L)	23.4 (4.30)	79.6 (40.6)	0.001
Glucose (mmol/L)	5.53 (0.40)	5.32 (1.06)	0.487
Insulin (mU/L)	9.67 (12.4)	42.7 (27.7)	0.005
HOMA-IR	2.27 (2.70)	10.2 (6.99)	0.016
hs-CRP (mg/L)	0.25 (0.49)	2.95 (3.33)	0.004

BMI: body mass index; ALT: alanine aminotransferase; AST: aspartate aminotransferase; HOMA-IR: homeostatic model assessment for insulin resistance, calculated as fasting glucose (mmol/L) × insulin (mU/L)/22.5; hs-CRP: high sensitivity C-reactive protein.