Fructose Induced Endotoxemia in Pediatric Nonalcoholic Fatty Liver Disease
Table 2
Baseline characteristics of the 8 adolescents with biopsy-proven NAFLD and the 7 healthy controls: study cohort 2.
Parameters, mean (SD)
non-NAFLD ()
NAFLD ()
value
Age, years
13.7 (2.22)
13.0 (2.73)
0.315
Male, (%)
5 (71.4)
8 (100)
0.104
BMI -score
0.18 (0.65)
2.29 (0.38)
0.001
Hepatic fat, %
1.02 (1.18)
22.0 (6.16)
0.001
ALT (U/L)
14.6 (2.51)
130 (63.2)
0.001
AST (U/L)
23.4 (4.30)
79.6 (40.6)
0.001
Glucose (mmol/L)
5.53 (0.40)
5.32 (1.06)
0.487
Insulin (mU/L)
9.67 (12.4)
42.7 (27.7)
0.005
HOMA-IR
2.27 (2.70)
10.2 (6.99)
0.016
hs-CRP (mg/L)
0.25 (0.49)
2.95 (3.33)
0.004
BMI: body mass index; ALT: alanine aminotransferase; AST: aspartate aminotransferase; HOMA-IR: homeostatic model assessment for insulin resistance, calculated as fasting glucose (mmol/L) × insulin (mU/L)/22.5; hs-CRP: high sensitivity C-reactive protein.