Research Article

Fructose Induced Endotoxemia in Pediatric Nonalcoholic Fatty Liver Disease

Table 3

Baseline characteristics of participants enrolled in the 4-week beverage trial: study cohort 3.

Parameters, mean (SD)Fructose ()Glucose () value

Age (years)14.6 (2.50) 13.3 (2.32)0.273
Male, (%)3 (37.5) 4 (50.0)0.614
Body weight (kg)86.1 (13.3) 81.3 (15.9)0.521
BMI -score2.32 (0.56) 2.01 (0.26)0.184
Hepatic fat (%)14.5 (5.73) 12.1 (4.82)0.382
ALT (U/L) 35.1 (20.5) 31.3 (18.6)0.698
AST (U/L) 32.1 (9.76) 32.9 (7.45)0.865
Triglycerides (mmol/L)161 (111) 175 (58.5)0.768
Cholesterol (mmol/L)166 (28.8) 170 (48.8)0.836
LDL (mmol/L)106 (32.5) 105 (38.6)0.967
HDL (mmol/L)45.1 (9.84) 45.0 (9.83)0.986
FFA (mmol/L)0.97 (0.24) 1.16 (0.51)0.342
Glucose (mmol/L)5.46 (0.85) 4.97 (1.59)0.461
Insulin (mU/L)30.0 (13.7) 31.4 (30.5)0.906
HOMA-IR7.17 (3.03) 7.23 (8.28)0.985
hs-CRP (mg/L)4.22 (3.03) 3.16 (2.54)0.242

ALT: alanine aminotransferase; AST: aspartate aminotransferase; LDL: low-density lipoprotein; HDL: high-density lipoprotein; FFA: free fatty acid; HOMA-IR: homeostatic model assessment for insulin resistance index, calculated as fasting glucose (mg/dL) × insulin (µU/L)/405; hs-CRP: high sensitivity C-reactive protein.