Histological Characterization of Biliary Intraepithelial Neoplasia with respect to Pancreatic Intraepithelial Neoplasia

Table 2

Immunoprofiles of premalignant lesions of the biliary tract and pancreas.

	Intraepithelial neoplasia		Intraductal papillary neoplasm		Mucinous cystic neoplasm
	BilIN	PanIN	IPNB	IPMN	Hepatic MCN	Pancreatic MCN
MUC1	+	+	+	+	+	+
MUC2	+	−	+	+	−	−
MUC5AC	++	++	++	++	++	++
CK20	−	−	+	+	−	−

The results of comparative analysis for biliary and pancreatic neoplasms in the present study and our previous report (10) are summarized. −: likely absent; +: occasionally present; ++: usually present. BilIN: biliary intraepithelial neoplasia; CK: cytokeratin; IPMN: intraductal papillary mucinous neoplasm; IPNB: intraductal papillary neoplasm of the bile duct; MCN: mucinous cystic neoplasm; PanIN: pancreatic intraepithelial neoplasia.