Research Article

Serum Cytokeratin-18 Is Associated with NOX2-Generated Oxidative Stress in Patients with Nonalcoholic Fatty Liver

Table 1

Clinical and biochemical characteristics of 209 subjects with NAFLD.

Variables

Age (ys)54.3 ± 12.0
Male (%)64.6
Body mass index (kg/m2)31.6 ± 5.6
Waist circumference (cm)108 (101/118)
Total cholesterol (mg/dL)199.9 ± 39.4
HDL cholesterol (mg/dL)46 (39/55)
Urinary 8-iso-PGF2α (pg/mg creatinine)714.4 ± 121.5
Fasting glucose (mg/dL)99 (92/115)
Fasting insulin ( IU/mL)13.5 (9.8/19.9)
HOMA-IR3.4 (2.4/5.7)
Triglycerides (mg/dL)142 (103/182)
-GT (IU/L)26 (18/43)
AST (IU/L)21 (18/27)
ALT (IU/L)28 (20/40)
Adiponectin (ng/mL)7.5 (5.3/12.0)
Cytokeratin-18 ( IU/mL)180 (148/190)
sNOX2-dp (pg/mL)60 (49/67)
Metabolic syndrome (%)67.6
Diabetes mellitus (%)31.1