Circulating MicroRNAs in Plasma of Hepatitis B e Antigen Positive Children Reveal Liver-Specific Target Genes

Table 3

MicroRNA plasma levels in children with CHB relative to healthy controls.

MicroRNA (hsa)	Sample	Mean Ct	SD	Fold change	SE	value
28-5p	HBeAg pos.	28.21	1.35	3.1	2.8–3.5	<0.001
	HBeAg neg.	29.89	1.80	1.0	0.9–1.1
	Control	29.39	1.34	1
30a-5p	HBeAg pos.	28.50	1.22	5.6	4.9–6.4	<0.001
	HBeAg neg.	30.55	1.07	1.6	1.3–2.0
	Control	30.80	0.65	1
30e-3p	HBeAg pos.	28.72	1.60	6.8	6.0–7.8	<0.001
	HBeAg neg.	30.77	1.36	2.9	2.5–3.3
	Control	31.34	1.25	1
378a-3p	HBeAg pos.	25.69	1.39	15.1	13.0–17.5	<0.001
	HBeAg neg.	27.88	0.93	4.0	3.3–5.0
	Control	29.43	0.71	1
548c-5p	HBeAg pos.	35.17	1.57	0.7	0.6-0.7	<0.001
	HBeAg neg.	35.43	1.94	0.9	0.8–1.0
	Control	34.40	1.46	1
574-3p	HBeAg pos.	27.30	1.48	7.8	6.8–9.0	<0.001
	HBeAg neg.	29.51	1.22	2.1	1.7–2.4
	Control	30.07	0.98	1
654-3p	HBeAg pos.	35.11	1.82	0.4	0.3–0.5	<0.001
	HBeAg neg.	34.68	2.16	0.7	0.6–0.8
	Control	33.62	1.94	1
let-7c	HBeAg pos.	27.24	1.53	7.4	6.5–8.5	<0.001
	HBeAg neg.	29.02	1.36	2.7	2.3–3.2
	Control	29.94	1.15	1