Clinical Study

Sofosbuvir Plus Daclatasvir in Treatment of Chronic Hepatitis C Genotype 4 Infection in a Cohort of Egyptian Patients: An Experiment the Size of Egyptian Village

Table 1

Relation between patients' age and baseline biochemical parameters and achievement of SVR.

Baseline data Response to Treatment
Nonresponder ()
Mean ± SD/median (IQR)
Responder ()
Mean ± SD/median (IQR)

Age48.86 ± 9.1748.57 ± 13.09
ALT (IU/l)24 (21–41)40 (26.75–60.25)
AST (IU/l)35 (20–56)40 (27–67)
S. albumin (g/dl)3.7 (3.3–4.2)4.1 (3.87–4.4)
Total bil. (mg/dl)0.7 (0.45–1)0.7 (0.5–0.9)
INR1.05 (1–1.19)1.05 (1–1.13)
HCV-RNA266591 (110000–3800000)220500 (45000–864307.25)
TLC (×103/mm3)5.9 (4.5–8.3)7 (4.85–8.35)
HGB (gm/l)12.63 ± 0.6412.94 ± 1.75
PLT (×103/mm3)186.29 ± 85.35233.61 ± 66.91
Creatinine (mg/dl)0.94 ± 0.210.87 ± 0.22

-test; –Whitney test; ALT: alanine transaminase, AST: aspartate transaminase, bil.: bilirubin, HGB: haemoglobin, INR: international normalized ratio, IQR: interquartile range, TLC: total leucocytic count, PLT: platelet.