Differential Effects in Cardiovascular Markers between High-Dose Angiotensin II Receptor Blocker Monotherapy and Combination Therapy of ARB with Calcium Channel Blocker in Hypertension (DEAR Trial)

Figure 1

Cardioankle vascular index (CAVI), augmentation index (AI), ankle-brachial index (ABI), maximum of intima-media thickness (MAX-IMT), urinary albumin to creatinine ratio (ACR), serum atrial natriuretic peptide (ANP), and serum brain natriuretic peptide (BNP) at baseline and after 12 months of treatment with olmesartan monotherapy (open circles) or combination therapy with olmesartan and azelnidipine (closed circles). *𝑃<.05 versus the baseline value. ^†𝑃<.05 versus the olmesartan monotherapy.

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