Table 1: Functions associated with ligand activation of the AT1, AT2, and Mas receptors.

AT1 receptor subtype
 Vasoconstriction
 Aldosterone release
 Vasopressin release
 Cardiac hypertrophy
 Fibrosis
 Proliferation
 Inflammation
 Platelet aggregation
 Oxidative stress
 Endothelial disruption

AT2 receptor subtype
 Vasodilation
 Antifibrotic
 Antiproliferative
 Antihypertrophic
 Antithrombotic

Mas receptor
 Vasodilation
 Antifibrotic
 Antihypertrophic
 Antithrombotic
 Promotes endothelial function