New Cardiovascular and Pulmonary Therapeutic Strategies Based on the Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas Receptor Axis

<table>Schematic representation of the renin-angiotensin system (RAS) cascade. The counterregulatory axes of the RAS are composed by ACE/Ang II/AT<sub>1</sub> and ACE2/Ang-(1–7)/Mas. ACE: angiotensin-converting enzyme; Ang: angiotensin; AT<sub>1</sub>: Ang II type 1 receptor; AT<sub>2</sub>: Ang II type 2 receptor; Mas: Ang-(1–7) receptor; PCP: prolylcarboxypeptidase; PEP: prolyl-endopeptidase; NEP: neutral-endopeptidase 24.11.</table>

International Journal of Hypertension

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Figure 1

Figure 1: New Cardiovascular and Pulmonary Therapeutic Strategies Based on the Angiotensin-Converting Enzyme 2/Angiotensin-(1–7)/Mas Receptor Axis 