Risk Factors Related to Low Ankle-Brachial Index Measured by Traditional and Modified Definition in Hypertensive Elderly Patients
Table 2
Clinical and laboratorial characteristics of the groups with normal (>0.9) and low (≤0.9) ankle-brachial index (ABI) obtained by AHA/TASC II standardization and by modified definition.
Characteristic
AHA definition
Modified definition
ABI > 0.9 ()
ABI ≤ 0.9 ()
value
ABI > 0.9 ()
ABI ≤ 0.9 ()
value
Age, years
NS
NS
Body mass index, kg/m2
NS
NS
Waist circumference, cm
NS
NS
Metabolic syndrome, (%)
22 (41%)
9 (75%)
<0.05
17 (38%)
14 (67%)
<0.05
CV diseases, (%)†
5 (9%)
7 (58%)
<0.001
3 (6%)
9 (42%)
<0.001
Diabetes, (%)
7 (13%)
10 (83%)
<0.01
9 (20%)
6 (29%)
<0.05
Smoker, (%)
11 (21%)
4 (33%)
NS
9 (20%)
6 (29%)
<0.05
Cardiovascular risk
(i) FRS ≥ 20%, (%)
20 (38%)
12 (100%)
<0.001
16 (36%)
18 (86%)
<0.001
(ii) FRS < 20%, (%)
33 (62%)
0 (0%)
<0.001
28 (63%)
3 (14%)
<0.001
LV hypertrophy, (%)
13 (24%)
5 (41%)
NS
10 (23%)
8 (38%)
NS
GFR, mL/min/1.73 m2
NS
NS
Fasting glucose, mg/dL
<0.05
<0.05
Total cholesterol, mg/dL
NS
NS
LDL-cholesterol, mg/dL
NS
<0.05
HDL-cholesterol, mg/dL
<0.05
0.01
Triglycerides, mg/dL
NS
NS
Uric acid, mg/dL
NS
NS
ABI, arbitrary units
<0.01
<0.001
Data are expressed as mean ± SEM or (%) when indicated. ABI: ankle-brachial index; CV: cardiovascular; FRS: Framingham risk score; LV: left ventricular; GFR: glomerular filtration rate; LDL: low-density lipoprotein; HDL: high-density lipoprotein; NS: nonsignificant. †Include coronary heart disease: stroke, or transitory ischemic accident.