Research Article

Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats

Figure 4

Effects of 3-day s.c. administration of 2.5 mg/kg of fulvestrant on the anandamide-induced reductions of contractile responses to NA in untreated (a), genisteintreated (10 mg/kg; (b)), or daidzein-treated (20 mg/kg; (c)) intact female rats. Either fulvestrant (filled circles) or its vehicle (open circles) were administered concomitantly with the corresponding phytoestrogen treatment. when phytoestrogen-treated were compared against phytoestrogen plus fulvestrant-treated intact female rats.
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(a)
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(b)
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(c)