Clinical Study

Clinical Implications of the Change in Glomerular Filtration Rate with Adrenergic Blockers in Patients with Morning Hypertension: The Japan Morning Surge-1 Study

Table 1

Baseline characteristics of patients.

 Added treatment group ( )Control group ( ) value

Age (years) 0.88
Male (%)45.143.60.76
Body mass index (kg/m2) 0.82
Duration of hypertension (years) 0.74
Duration of hypertensive therapy (years) 0.34
Current smokers (%)19.218.81.00
Habitual drinkers (%)34.130.0 0.32
Diabetes or impaired glucose tolerance (%)15.316.50.76
Hyperlipidemia (%)32.540.90.04
Number of antihypertensive drugs 0.71
Calcium channel blockers (%)66.665.60.82
Angiotensin-converting enzyme inhibitors (%) 13.115.60.37
Angiotensin II receptor blockers (%)60.357.50.54
Diuretics (%)22.0 21.90.93
Oral drugs for diabetes mellitus (%)9.57.60.51
Medication for hyperlipidemia (%)15.113.60.62
Office SBP (mmHg) 0.43
Office DBP (mmHg) 0.92
Office pulse rate (bpm) 0.11

Data are shown as the means ± SD. Urinary albumin values are expressed as the median (25% value, 75% value). BP: blood pressure; bpm: beats per minute; SBP: systolic blood pressure; DBP: diastolic blood pressure.