Role of Renal Nerves in the Treatment of Renovascular Hypertensive Rats with L-Arginine
Figure 1
(a) Systolic blood pressure data measured by tail cuff in renovascular hypertensive rats (time 0: baseline before surgery, 7th day after surgery and/or denervation, and 14th day after surgery and/or denervation and L-arginine treatment). (b) Mean arterial pressures at the end of experiment in conscious rats for all experimental groups (SHAM: normotensive control; 2K1C: two-kidney one-clip; 2K1C + L-arg: two-kidney one-clip treated with L-arginine; DN: denervated normotensive; 2K1C + DN: denervated two-kidney one-clip; and 2K1C + DN + L-arg: denervated two-kidney one-clip treated with L-arginine). The results are expressed as mean ± SEM. versus SHAM; versus 2K1C; versus DN; versus 2K1C + L-arg; versus 2K1C + DN, and versus 2K1C + DN + L-arg (Tukey test).
