Blood Pressure Response to Zofenopril or Irbesartan Each Combined with Hydrochlorothiazide in High-Risk Hypertensives Uncontrolled by Monotherapy: A Randomized, Double-Blind, Controlled, Parallel Group, Noninferiority Trial

Figure 3

Mean office systolic blood pressure (SBP) and diastolic blood pressure (DBP) values and changes with treatment () in patients treated with zofenopril 30–60 mg plus hydrochlorothiazide 12.5 mg (open bars) or irbesartan 150–300 mg plus hydrochlorothiazide 12.5 mg (full bars). Data are shown for the intention-to-treat population and as mean values ±SD. Asterisks refer to the statistical significance of the intertreatment differences (; ).