Genetic Variants of C-5312T REN Increased Renin Levels and Diastolic Blood Pressure Response to Angiotensin Receptor Blockers

Table 4

Genetic variants of the REN and reduction in blood pressure (valsartan therapy).

REN C-5312T	SBP (mmHg)			DBP (mmHg)
	Baseline	ARB		Baseline	ARB
CT/TT	155.2 ± 15.3	135 ± 13.6	0.56	93.20 ± 15.5	83.2 ± 13.6	0.04
CC	140.65 ± 19.03	120.5 ± 20.5		92.45 ± 15.23	80.1 ± 14.6

Data are means ± SD. Statistical analysis of the difference was performed by independent -test as appropriate. value was calculated for the statistics showing the interactive effect of ARB administration and category in patients on DBP.