Changes in Angiotensin Receptor Distribution and in Aortic Morphology Are Associated with Blood Pressure Control in Aged Metabolic Syndrome Rats
Table 1
Characteristics and biochemical parameters from control and MS rats during aging.
Groups and age (months)
Body weight (g)
Central adiposity (g)
Blood pressure (mm Hg)
Glucose (mM)
Triglycerides (mg/dL)
Insulin (U/mL)
HOMA-IR
Control
6
517.1 ± 6.7
6.2 ± 0.9
101.6 ± 0.9
5.0 ± 0.9
50.9 ± 5.2
5.9 ± 1.3
1.9 ± 0.7
12
580.2 ± 9.6
10.3 ± 1.4
100.0 ± 1.8
5.1 ± 0.4
96.1 ± 4.3
6.1 ± 2.4
2.0 ± 0.9
18
620.9 ± 10.4‡
14.4 ± 3.1
106.1 ± 1.1
5.4 ± 0.8
149.7 ± 6.9‡
6.4 ± 0.9
1.7 ± 0.9
MS
6
535.7 ± 12.3
14.7 ± 0.8†
148.6 ± 1.2†
4.9 ± 0.9
113.3 ± 10.4†
22.4 ± 5.2†
4.7 ± 2.1†
12
650.7 ± 17.4
19.9 ± 2.1†
115.2 ± 5.6
5.9 ± 0.1
198.6 ± 25.7
19.6 ± 8.1
4.5 ± 1.7
18
806.3 ± 18.7†‡
43.3 ± 5.2†‡
100.1 ± 2.1‡
6.1 ± 0.4
271.3 ± 31.4
6.9 ± 2.3
1.9 ± 0.6
Values are means ± SEM.; HOMA-IR: homeostatic model assessment of insulin resistance; ; against C; versus C; against other ages in corresponding group; against 6 months in corresponding group.