Early- and Late-Onset Preeclampsia: A Comprehensive Cohort Study of Laboratory and Clinical Findings according to the New ISHHP Criteria
Table 6
Laboratory measurements in women with early-onset and late-onset preeclampsia.
EOP (n), mean ± SD
LOP (n), mean ± SD
Proteinuria (g/L)
(n = 80) 4.21 ± 6.84
(n = 58) 2.32 ± 3.61
0.007
Proteinuria, n (%)
(91)
(78)
≤5 g/day, n (%)
53 (58.2)
59 (75.6)
ns
5.1–9.9 g/day, n (%)
16 (17.6)
10 (12.8)
ns
≥10 g/day, n (%)
22 (24.2)
9 (11.6)
0.0122
24-hour urine proteinuria (g/24 h)
(n = 91) 6.35 ± 8.23
(n = 78) 3.82 ± 4.36
0.008
Blood urea nitrogen (mmol/L)
(n = 75) 5.31 ± 1.93
(n = 62) 4.88 ± 3.14
0.021
Uric acid (µmol/L)
(n = 30) 418.1 ± 107.6
(n = 25) 389.6 ± 82.3
ns
Creatinine (µmol/L)
(n = 78) 72.3 ± 31.2
(n = 56) 63.0 ± 34.4
0.001
Creatinine clearance (ml/min)
(n = 16) 102.8 ± 48.0
(n = 15) 127.8 ± 74.1
ns
Total serum protein (g/L)
(n = 71) 55.8 ± 6.0
(n = 48) 57.7 ± 7.21
ns
Albumin (g/L)
(n = 50) 29.2 ± 4.28
(n = 30) 31.5 ± 6.74
ns
Hemoglobin (g/L)
(n = 113) 12.3 ± 1.49
(n = 92) 12.3 ± 1.33
ns
Hematocrit (%)
(n = 113) 35.6 ± 4.3
(n = 92) 35.8 ± 3.7
ns
Erythrocytes (×109/L)
(n = 113) 4.05 ± 0.47
(n = 92) 4.04 ± 0.42
ns
Platelet (×109/L)
(n = 113) 184.0 ± 72.8
(n = 92) 178.0 ± 68.9
ns
Alanine aminotransaminase (U/L)
(n = 73) 43.4 ± 48.2
(n = 50) 70.9 ± 141.0
ns
Aspartate aminotransferase (U/L)
(n = 73) 44.8 ± 53.3
(n = 50) 65.2 ± 134.9
ns
The values in indicate number of performed measurements; EOP, early-onset preeclampsia; LOP, late-onset preeclampsia; ns, nonstatistically significant; SD, standard deviation.
